Akne: FDA genehmigt Aczone für Akne-Behandlung

Die US-Food and Drug Administration (FDA) genehmigt Aczone (Dapson) Gel, 5 Prozent für Akne vulgaris topische Behandlung auf den Markt. Aber Patienten, die die Enzymmangel haben, G6PD (Glucose-6-Phosphat-Dehydrogenase), müssen mit regelmäßigen Blutwerte überwacht werden, um festzustellen, ob sie auf eine Art von Anämie (hämolytische Anämie) veranlagt sind.
Aczone, eine Marke der QLT USA Inc., ist eine wässrige topische Gel, das 5 Prozent Dapson enthält. Nach der wissenschaftlichen Forschung, ermöglicht dapsone topisch und sicher angewendet werden Dapson in einem Lösungsmittel Mikroteilchen (SMP) Gel kombiniert. Dieses Produkt erreicht bedeutenden Prozent Verringerung der Zahl der Akne-Läsionen und bessere Erfolgsquote auf dem globalen Akne Beurteilung Score in zwei randomisierten, doppelblinden, Fahrzeug kontrollierten klinischen Studien in 3000 Akne-Patienten.
Fettigkeit / Peeling, Trockenheit und Erythem waren die häufigsten unerwünschten Ereignisse aus kontrollierten klinischen Studien berichtet. Allerdings gab es keine signifikanten Unterschiede in der Rate unerwünschter Ereignisse zwischen Aczone Gel und Fahrzeugkontrolle behandelten Patienten.
1,4 Prozent von etwa 3500 Patienten hatten die Enzymmangel -im Aczone klinischen Studie programmier-, die mit der Häufigkeit in der allgemeinen nordamerikanischen Bevölkerung in Einklang steht.
Das Unternehmen QLT wird eine post-Zulassung Phase IV-Studie in 50 Akne-Patienten verpflichten sich, die G6PD-Mangel haben und ihnen zu folgen für 6 Monate, nach denen QLT einen Antrag bei der FDA einreichen erwartet, dass die Aczone Etikett neu zu bewerten.
Der Präsident und Chief Executive Officer von QLT Inc., Paul Hastings, erklärte, dass "Aczone eine wichtige klinische Fortschritt in der Dermatologie stellt, hat in mehr als 4.000 Patienten Sicherheit und Wirksamkeit unter Beweis gestellt. Wir sind sehr zufrieden mit der FDA-Entscheidung und zuversichtlich in Aczone Potenzial als neue Klasse zur Behandlung von Akne-Patienten ".

Akne: Ein Erwachsener Dilemma als auch

Akne wird oft als ein wichtiger Teenager Problem angesehen. Zwar gibt es einige Erwachsene, die leidet auch von dem, was wir "Erwachsenen-Akne" nennen. Erwachsene in ihren Zwanzigern und darüber hinaus noch Akne auftreten, und die negativen Auswirkungen von Stress erhöht die Belastung der es in ihrem Gesicht auftauchen müssen.
Studien zeigen, dass psychische Stress eine der Hauptursachen bei der Entwicklung von Akne für Erwachsene sein kann. Darüber hinaus sind Frauen wahrscheinlich von ihm zu leiden, weil sie mehr Stress ausgesetzt sind, die sie während ihrer täglichen Lebensstil zu erwerben. Sie sind auch anfällig für hormonelle Störungen, vor allem in Zeiten, in denen sie ihre monatlichen Menstruation und während der Schwangerschaft haben.
Die Umgebung ist ein weiterer Faktor bei der Entwicklung von Erwachsenen Akne. Wenn Ihre Umgebung immer schmutzig sind, höchstwahrscheinlich alle Staub wird durch den Wind erfolgen und schließlich auf Ihrem Gesicht landen. Wenn ungewaschen gelassen wird, kann diese von Staub und Schmutz verstopfen die Poren und infizieren sie die Pore entzündet zu machen.
Genau wie jugendlich Akne, die beste Behandlung, die Sie ist die Aufrechterhaltung richtige Hautpflege und eine gesunde Körperpflege in Anspruch nehmen kann. Nehmen Sie ein Bad jeden Tag, und einer milden Seife verwenden nur so, dass Ihre Akne wird nicht weiter in eine Infektion zu entwickeln.
Achten Sie auch auf Ihre Ernährung. Trinken Sie genug Wasser und ausschließen von dem Essen ein paar fettige Lebensmittel. Essen Sie mehr Obst und Gemüse.
Nehmen Sie sich ausreichend Schlaf und Ruhe. Es wird Ihre Poren der Haut entspannen und schließlich Akne von der Entwicklung zu verhindern.
Der Lebensstil eines Erwachsenen ist ein wichtiger Faktor im Erscheinungsbild der Erwachsenen Akne als auch. Vermeiden Sie trinken Alkohol, alkoholhaltigen Getränken und das Rauchen. Es wird nur mit Akne Gesicht gespickt machen.
Sie können auch einige Akne Medikamente wie Hautpflege-Produkte und Hautbehandlungen nehmen. sehen Sie Ihre Dermatologe, so dass er / sie kann feststellen, welche Behandlung die richtige für Sie sein würde.

Beautiful Skin Made Easy With Simple Aromatherapy Blends

Looking for that perfect skin product? One that will keep your skin looking great, smells great, is appealing to apply, has actual 'therapeutic' effects, and doesn't break the bank? Look no further than aromatherapy. Creating a wonderful blend just for your skin type with the magic of potent natural botanicals is fun and rewarding in more ways than one. Essential oils are widely used in natural medicine, and some are well-known for their skin rejuvenating effects.

While some of the most highly regarded therapeutic grade oils may seem expensive at first, they are effective in such small concentrations as to really make them worthwhile. And their efficacy is well-known; that's why so many laboratory-made preparations use components of essential oils in their formulas. With a one or two ounce bottle to mix in, and an eye dropper, you can easily mix your own blend with the aroma and actions you desire most.

There are a few essential oils most often used in skin care recipes – you can pick and choose from among these depending on your desired results. Other essential oils may be added to enhance the aroma of your blend; many oils used to do so are also are know to relieve tension or bring about a healthy state of mind – and most natural clinicians will tell you that beauty starts from the inside-out. So make something you love the smell of that also helps your skin glow!

These few primary skin care oils include the following: Helichrysum italicum – the oil of this flower is one of the most highly regarded in aromatherapy for it's great versatility. It has a pleasant aroma, it contains rare 'di-ketones' which stimulate the skin's natural metabolism, and is a powerful anti-inflammatory (all tissue damage and aging is associated with inflammation on a cellular level). Lavender oil – 'true' or 'French' Lavender is the most used oil in aromatherapy today because of it's great multitude of effects. Like Helichrysum, it contains regenerative ketones; it reduces inflammation; it speeds wound healing; AND it has an aroma very well known for its relaxing effects – easing tension while healing your skin – could you ask for more? Next up is Rosemary of the 'verbenone' type. It also contains ketones (that the cineol type does not) and is known as a circulatory and metabolism stimulant, increasing the flow of nutrients in, and waste products out, of your skin cells. Palmarosa essential oil is included in many blends for it's gentle cleansing and antiseptic properties. And last but not least, Carrot Seed oil is the premier oil for regenerating tired, lifeless skin – often a result from too much stress or high levels of pollutant exposure.

There are several other oils with positive effects on the skin (some will be mentioned in the blends below), these just happen to be the most often used. With research, you can find essential oils that will address particular skin conditions that are not covered here. Further, there are in fact hundreds of essential oils available, each with it's own unique composition and aroma. Adding a little to your blends simply for their fragrance influence is highly recommended. A few drops of precious oils like Jasmine, Neroli, Sandalwood or Rose can create that aromatic combination you simply love, and will want to wear all the time.

The essential oils are almost never applied to the skin undiluted (Lavender is a rare exception). Instead, they are added to what are known as 'carrier' or 'base' oils. Diluting the essential oil in carrier not only stretches your dollar, but the oils actually are more effective this way! Research has shown that most essential oils have the most dramatic therapeutic effects at concentrations of less than 5% of the total blend. And the carriers have their own positive effects; besides helping your skin absorb the essential oils, they provide nutrients such as essential fatty acids, and vitamin compounds which enhance the skin's health.

Some of the more commonly used carrier oils in skin care are as follows: First is Hazelnut oil – pressed from, obviously, Hazelnuts. This is considered the most gentle of the carrier oils, suitable for all skin types. It often serves as the primary base oil in blends, making up a majority of the mixture. Next is Rosehip seed oil, pressed from Rosehip seeds grown in the mountains of South America. This well researched oil not only has a wealth of essential fatty acids, but contains trans-retinoic acid, a compound similar to the active ingredient of Retin-A (a well known wrinkle cream), but without the drying side effects. Lastly we'll mention Evening Primrose oil, often included in blends for aging skin and for eczema – it has one of the highest known concentrations of gamma-linolenic acid (GLA), an essential fatty acid which may be crucial to optimal health.

So there are the primary ingredients, and the reasons behind them. With these, and a few of your own personal touches, you can create a great variety of blends. To go ahead and start mixing, acquire a one or two ounce dark glass bottle to mix in, an eye dropper and a small funnel (you don't NEED this, it just makes the whole process a lot less messy). For the first recipe, we'll start with a blend that's for daily use for all skin types. It's created to give the skin health and vitality, while keeping it clean and beautiful: Pour one ounce of Hazelnut oil into your mixing bottle (double all the ingredients if you'd like to make two ounces). Add fifteen drops (about 2/3rds of a milliliter) Thyme essential oil of the Linalool chemotype (be sure to get this kind, as other types of Thyme are to strong to use on the skin). The add fifteen drops each of Rosemary verbenone, Neroli (or a high-quality Petitgrain – distilled from the same plant as Neroli with a lower cost), Spike Lavender (almost a cross between true lavender and sage – excellent for it's antiseptic properties). While originally created as an acne-clearing blend, it did so well for so many folks it is now used as a basis for healthy 'normal' skin as well.

For overly sensitive and damaged skin (from chemicals or other means) and for skin with weak capillaries (showing spider veins may be a symptom), start with a 5:1:1 ratio of Hazelnut, Rosehip Seed and Evening Primrose oils (3/5 ounce Hazelnut, and 1/5th each of the other oils). Add fifteen drops each of German Chamomile, Helichrysum italicum, true Lavender, and Roman Chamomile. This blend will enhance the regenerative capability of the skin through the action of the Helichrysum and Rosehip seed, provides nutrients through in the Rosehip seed and Evening Primrose, and reduces the inflammation which accompanies any type of damage and aging.

For clearing excessively oily and acne-prone skin, to one oz. of Hazelnut oil, add fifteen drops each of Myrtle essential oil (use the green, rather than red, variety), Eucalyptus Dives, Spike Lavender, and Rosemary verbenone. The Myrtle is special in that it dissolves the sebum clogging skin pores, and the Eucalyptus calms the output of the sebaceous (oil-producing) glands.

If your skin has no particular 'condition', but appears tired, lifeless, pallid, or 'worn out', try mixing one-fifth ounce of Rosehip Seed and four-fifths ounce Hazelnut oil. Then add 15 drops each of Carrot Seed essential oil (also known as Queen Anne's Lace or Wild Carrot), Lemon verbena (which helps the skin detoxify), Niaouli (gently tightening the skin), and Rosemary verbenone – this creates an excellent restorative blend. For aging skin needing firming that can be used around the eyes – try this more gentle variety: Mix in five ounces of Hazelnut oil and one ounce of Rosehip seed oil, add fifteen drops of each of Myrtle essential oil (green), Cistus or Rock Rose and Rosemary.

So there are a few tried-and-true aromatherapy skin care blends to use in your natural beauty regime. You can easily mix and match the oils described to create your own blend, and add any oils you really like the aroma of (be aware that a FEW essential oils are VERY strong, and should not be used on the skin – the more common of these include Cinnamon, Clove, Oregano, and Red Thyme – consult with a knowledgeable practitioner if you are unsure about the safety of any oil). A word about purchasing oils for your blends – do NOT use anything labeled as a 'fragrance oil' – these are synthetic reproductions of essential oils that will likely cause an allergic reaction. DO seek out a reputable source. And oils, like wine, do vary greatly from maker to maker. A higher price can mean a significantly nicer oil (though not always) – one that is sweeter, or more well-rounded – only a few oils should smell 'medicinal' – Spike Lavender is a little 'camphorus' in general – but a good Rosemary verbenone should have a very appealing scent . Despite the initial outlay, you are more likely to continue to use a blend that you really like the aroma of, and that has therapeutic effects. Though once you find the oils you adore, you're more than likely to continue the practice of making your own blends for some time to come.

Acne Prevention - Hygiene and Medication

Proper Hygiene

One of the most common misconceptions about acne is that it's caused by dirt. It's not! Acne is caused by a combination of factors you can't control, like your hormone balance and the natural pace of your skin's renewal system. Fortunately, there are a number of things you can control that may help you keep your acne in check. Begin by following these simple suggestions for healthy-skin hygiene.

Acne Prevention - Tip #1: Don't over-wash. Since dirt is not causing your acne, excessive scrubbing and washing won't make it go away. Try to limit yourself to two washings per day — anything more than that can leave your healthy skin dry, and your acne-prone areas irritated. Habitual over-washing may also stimulate extra oil production, which could result in more breakouts. 

Acne Prevention - Tip #2: Skip harsh scrubs. It's okay to exfoliate, but be sure to use a gentle formula with small, smooth grains. Avoid products with almond or apricot shell fragments; they can irritate or even tear your skin and further aggravate your acne. 

Acne Prevention - Tip #3: Say no to alcohol. If you use a toner, avoid products with high concentrations of isopropyl alcohol, or common rubbing alcohol. A strong astringent, alcohol strips the top layer of your skin, causing your sebaceous glands to produce more oil. The result? Dry, red skin — and possibly more blemishes.

Acne Prevention - Tip #4: Don't squeeze or pick. Squeezing or picking your blemishes — with fingernails, pins or anything else — can force bacteria deeper into the skin, causing greater inflammation and infection. You'll also increase the damage to the surrounding skin, so the blemish is more likely to leave a permanent acne scar. 

Acne Prevention - Tip #5: Hands off! Propionibacterium acnes (the bacteria that causes breakouts) is a normal resident of your skin; it doesn't lead to acne until it gets trapped inside the hair follicle. Excessive touching of your face, including rubbing or even resting your chin in your hands, can drive bacteria into your pores — where it can begin its dirtywork. 

Acne Prevention - Tip #6: Work out, wash off. When you exercise, your movement generates heat; clothing and equipment cause friction. Until you shower off, heat and moisture are trapped against your skin, creating an ideal breeding ground for the spread of bacteria. So whenever you can, shower off immediately after exercising. 

Acne Medications

Acne Prevention Treatment - Find a regimen and stick with it. Most cases of mild acne can be improved with "over-the-counter" products, or products that don't require a prescription from your doctor. There is a wide range of treatments available, and there’s a good chance one of them will work for you. If you start treatment before your acne gets severe, you’ll have a better chance of avoiding physical and emotional problems down the road. But if your acne gets worse or lasts more than a couple of weeks, see a dermatologist. Here's a quick listing of the most common products used to treat acne — click on the links that interest you for more information on that course of acne treatment.

• Benzoyl Peroxide: Kills the bacteria that causes acne.

• Proactiv® Solution: A dermatologist formulated Combination Therapy® acne management system. Click Here and receive 2 free bonuses when you try Proactiv® Solution Risk-Free for 60 Days!

• Salicylic Acid: Unclogs your pores and encourages skin renewal.

• Tretinoin (Retin-A®): Promotes healthy sloughing.

• Antibiotics: Kill bacteria and reduces inflammation.

• Oral Contraceptives: Help regulate hormone levels.

• Anti-Androgens: Inhibit the body's production of acne-causing hormones.

• Isotretinoin (Accutane®): Treatment for severe cystic or nodular acne.

There are a number of prescription medications known to cause acne. If you routinely take any of the following drugs (or drugs like them) and have problems with acne breakouts, you may want to consult your physician to discuss an alternative treatment with fewer side affects. But try to keep it in perspective, your health comes first!

Anticonvulsants (like Dilantin) are prescribed for the treatment of epilepsy and other kinds of seizures. Most medications in this family list acne as a common side-effect. 

Corticosteroids (like Prednisone) are often used to treat asthma and other chronic lung diseases. Like cortisol, a natural steroid produced by the body during times of intense stress, corticosteroids can stimulate sebum production and lead to blemishes.

Disulfuram (or Antabuse) is prescribed to help chronic alcoholic patients who want to remain in a state of enforced sobriety. When mixed with alcohol, this drug causes a range of unpleasant symptoms intended to discourage further mixing. Unfortunately, regular use of Disulfuram (even when not drinking) can cause acne in some patients.

Immuran. Like other immunosuppressants, Immuran is used to suppress the immune system in patients awaiting an organ transplant. It can help prevent organ rejection; it can also suppress your body’s natural ability to fight the bacteria that cause acne. 

INH (or Isoniazid) is typically used to treat tuberculosis, or TB. Thought to be largely eradicated, TB experienced a resurgence in the late 1980s among the homeless population and in patients suffering from AIDS. It continues to be a problem today.

Quinine is prescribed as a precaution against — or treatment for — malaria. If you’re traveling to a part of the world where malaria is a risk, be sure to ask your doctor about alternative solutions.

Thyroid preparations. Some thyroid medications (such as Thiourea and Thiouracil) are known to trigger acne. These preparations are used to stimulate the thyroid gland in patients with low thyroid function. Large amounts of iodine, which also helps to regulate thyroid function, can also cause breakouts.